Chronic sclerosing sialadenitis as the initial manifestation of the IgG4-related sclerosing disease
نویسندگان
چکیده
Three Chinese patients, one female aged 63 years, two males aged 52 and 54 years, respectively, all presented with chronic sclerosing sialadenitis (CSS) as the initial clinical manifestation, followed by IgG4-related sclerosing pancreatitis. The kidneys and lungs were involved in case 1. Moreover, enlargement of hilar lymph nodes was also noted in this patient. After steroid therapy, the clinical symptoms alleviated in all three patients.
منابع مشابه
Unusual Involvement of IgG4-Related Sclerosing Disease in Lacrimal and Submandibular Glands and Extraocular Muscles
Chronic sclerosing sialadenitis, also known as Kuttner tumor, is a chronic inflammatory disease of the salivary glands that is reported in a few cases in medical literature. Recent reports suggest that certain aspects of sclerosing diseases, including chronic sclerosing sialadenitis or dacryoadenitis, should be classified under immunoglobulin G4 (IgG4)-related sclerosing disease based on immuno...
متن کاملChronic sclerosing sialadenitis of the submandibular gland: an entity of IgG4-related sclerosing disease.
Chronic sclerosing sialadenitis typically involves the submandibular gland. It usually occurs in the middle-aged and elderly adults with a slight male predominance. Recent evidences have suggested that it is an entity of IgG4-related sclerosing disease and has distinct histopathological features, such as a dense lymphoplasmacytic infiltrate, sclerosis and obliterative phlebitis. It is important...
متن کاملClinicopathology of Immunoglobulin G4-Related Chronic Sclerosing Sialadenitis: A Single-Center Study.
OBJECTIVES To investigate the clinicopathologic characteristics of patients with immunoglobulin G4-related chronic sclerosing sialadenitis (IgG4-RCSS), a recently recognized disease. STUDY DESIGN Case series with chart review and pathology study. SETTINGS Tertiary care hospital. SUBJECTS AND METHODS We evaluated chronic sialadenitis specimens obtained over 11 years using pathologic examin...
متن کاملIgG4 related sclerosing sialadenitis- a retrospective analysis.
BACKGROUND IgG4 related disease rarely affects the salivary glands and clinically is often confused with salivary gland malignancy. METHOD This is a retrospective study comprising 137 cases of chronic sialadenitis diagnosed in a histopathology department over 4 years. The morphology was assessed by reviewing the histology slides and the incidence of IgG4 related sclerosing sialadenitis was ca...
متن کاملNonspecific interstitial pneumonia with abundant IgG4-positive cells infiltration, which was thought as pulmonary involvement of IgG4-related autoimmune disease.
Recently, great attention has been drawn to IgG4-related diseases such as autoimmune pancreatitis (AIP) sclerosing sialadenitis, retroperitoneum fibrosis, sclerosing cholangitis. IgG4-related diseases are characterized by high serum IgG4 concentrations, sclerosing inflammation with numerous IgG4-positive plasma cells, and steroid sensitivity irrespective of their organs of origin. In this repor...
متن کامل